Drugs, lipid metabolism, and atherosclerosis [proceedings] by International Symposium on Drugs Affecting Lipid Metabolism (6th 1977 Philadelphia, Pa.)

Cover of: Drugs, lipid metabolism, and atherosclerosis | International Symposium on Drugs Affecting Lipid Metabolism (6th 1977 Philadelphia, Pa.)

Published by Plenum Press in New York .

Written in English

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Subjects:

  • Arteriosclerosis -- Chemotherapy -- Congresses.,
  • Lipids -- Metabolism -- Congresses.,
  • Antilipemic agents -- Congresses.,
  • Lipoproteins -- Metabolism.,
  • Metabolism -- Drug effects.,
  • Lipids -- Metabolism.,
  • Arteriosclerosis -- Drug therapy.,
  • Arteriosclerosis -- Metabolism

Edition Notes

Book details

Statementedited by David Kritchevsky, Rodolfo Paoletti, and William L. Holmes.
SeriesAdvances in experimental medicine and biology ;, v. 109
ContributionsKritchevsky, David, 1920-, Paoletti, Rodolfo., Holmes, William L., 1918-, Council on Arteriosclerosis (American Heart Association)
Classifications
LC ClassificationsRC692 .I54 1977
The Physical Object
Paginationxi, 443 p. :
Number of Pages443
ID Numbers
Open LibraryOL4726438M
ISBN 100306400529
LC Control Number78014222

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Drugs, Lipid Metabolism, and Atherosclerosis (Advances in Experimental Medicine and Biology) [Kritchevsky, David] on *FREE* shipping on qualifying offers. Drugs, Lipid Metabolism, and Atherosclerosis (Advances in Experimental Medicine and Biology).

About this book This volume comprises the proceedings of the sixth International Symposium on Drugs Affecting Lipid Meta­ bolism.

Since the first of these symposia in these triennial meetings have been devoted to the exploration of new ideas, new data and new concepts related to lipid metabolism and atherosclerosis.

The action of drugs on arterial and HDL metabolism was also discussed as were newer aspects of platelet aggregation, especially as related to prostaglandins.

New ground was also broken in discussions of lipid mobilization and mechan­ isms of hypocholesteremia. Get this from a library. Drugs, lipid metabolism, and atherosclerosis: [proceedings]. [David Kritchevsky; Rodolfo Paoletti; William L Holmes; Council on Arteriosclerosis (American Heart Association);] -- This volume comprises the proceedings of the Sixth International Symposium on Drugs Affecting Lipid Metabolism.

Since the first of these symposia in these triennial meetings have. This volume comprises the proceedings of the sixth International Symposium on Drugs Affecting Lipid MetaƯ bolism. Since the first of these symposia in these triennial meetings have been devoted to the exploration of new ideas, new data and new concepts related to lipid metabolism and atherosclerosis.

Mechanisms of Action and Physiologic Response: These agents stimulate the nuclear receptor peroxisome proliferator-activated receptor α, increasing the expression of many proteins involved in lipid metabolism. They stimulate HSL in muscle and thus, catabolism of triglyceride rich lipoproteins such as VLDL.

Lp (a) is a subclass of LDL and elevated Lp (a) is an independent risk-factor, primarily genetically mediated. Genetic data support that high Lp (a) causes atherosclerosis. Elevated triglycerides in plasma are associated with increased and atherosclerosis book for CVD. The recent symposium and the appearance of this new book on Drugs Affecting Lipid Metabolism take place at a very unusual time for the development of this area.

After the publication and wide acceptance of the results of the cholestyramine study by the Lipid Clinics in the USA, showing for the. Monoclonal antibodies targeting PCSK9 provoke significant lowering of LDL-C, non-high-density lipoprotein cholesterol and lipoprotein(a) as monotherapy or in combination with other lipid-lowering drugs.

In fact, only two PCSK9 inhibitors are clinically available: alirocumab and : Antoni Martínez-Rubio, Román Freixa Pamias. Several medications and medication classes have been reported to affect the lipid profile (Table 1).

In some cases, this is a class effect, and some agents belonging to the same class can have significantly different actions on lipid levels (e.g. beta blockers).4 This is a consideration to appreciate when selecting a specific agent for high-risk patients and concurrent medications known to Cited by: 2.

Cholesterol and its oxidized forms are major lipid species in the human atherosclerotic plaques. • Understanding cholesterol metabolism in the atherosclerotic plaques has contributed to the intervention of atherosclerosis. Summary Points • An elevated level of the plasma cholesterol increases the risk of CVD.

•Author: Young-Hwa Goo. Find many great new & used options and get the best deals for Drugs, Lipid Metabolism, and Atherosclerosis by Kritchevsky, David at the best online prices at. David Kritchevsky has 43 books on Goodreads with 11 ratings. David Kritchevsky’s most popular book is Dietary Fats, Lipids, Hormones, and Tumorigenesis.

and atherosclerosis book The Proceedings of the Eight International Symposium on Drugs Affecting Lipid Metabolism (8th D.A.L.M.) is the subject of this volume. Since the first symposium ineach successive meeting has broken new ground in the field of pharmacological control of lipid levels - offering new and stimulating insights and exposing the audience to the state of the : Paperback.

Drugs and lipid metabolism - Volume 33 Issue 3 - Truswell A. To send this article to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon by: 3.

The Proceedings of the Eight International Symposium on Drugs Affecting Lipid Metabolism (8th D.A.L.M.) is the subject of this volume. Since the first symposium ineach successive meeting has broken new ground in the field of pharmacological control of lipid levels - offering new and stimulating insights and exposing the audience to the state of the art.

Publisher Summary. Lipid modifications of proteins are widespread and functionally important in eukaryotic cells. Intracellular proteins such as the signal-transducing heterotrimeric GTP-binding proteins (G proteins) and the Ras superfamily of G proteins are modified by or carbon fatty acids and/or or carbon isoprenoids.

Purchase Hormones, Lipoproteins and Atherosclerosis - 1st Edition. Print Book & E-Book. ISBN  Accumulating evidence suggests that astaxanthin could exert cardioprotective actions by improving oxidative stress, inflammation, lipid metabolism, and glucose metabolism.

The objective of this review is to summarize the findings regarding the bio-functions of astaxanthin in the prevention of by: The liver plays a central role in metabolism of nutrients, synthesis of glucose and lipids, and detoxification of drugs and xenobiotics.

The major pathways in the liver are glucose, fatty acids. Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a common main feature of chronic hyperglycemia that results from defects of insulin secretion, insulin action, or both.

Insulin is an important anabolic hormone, and its deficiency leads to various metabolic abnormalities in proteins, lipids, and carbohydrates. Atherosclerosis develops as a result of a Author: Anastasia Poznyak, Andrey V.

Grechko, Paolo Poggio, Veronika A. Myasoedova, Valentina Alfieri, Alexa. This supplemental issue of Nutrients focuses on advances in "Lipid and Lipoprotein Metabolism as a Risk for Atherosclerosis". The scope of topics of interest extends to diet and drugs with emphasis on mechanisms of action on their hypolipidemic effects.”.

Advances in Experimental Medicine and Biology [01 Jan]Author: Sinclair H. Lipids module 1: lipid metabolism and its role in atherosclerosis. (see module 4 for more on CETP inhibitors as a drug class).

Nascent HDL, in the form of flattened discs, is generated from LPL- mediated lipolysis of triglyceride rich lipoproteins (TRLs,) including (VLDL and cChylomicrons), or triglyceride rich lipoproteins (TRLs) or. Title:Exosomes in Cholesterol Metabolism and Atherosclerosis VOLUME: 17 ISSUE: 3 Author(s):Allison B.

Reiss, Nicholas A. Vernice, Nicolle M. Siegart, Joshua De Leon and Lora J. Kasselman* Affiliation:Winthrop Research Institute and Department of Medicine, NYU Winthrop Hospital, Mineola, NYWinthrop Research Institute and Department of Medicine, NYU Winthrop Cited by: 6.

Through the interaction with diverse ligands, CD36 can modulate multiple physiologic and pathologic processes, including FA transport and lipid metabolism, scavenger receptor functions (e.g. uptake of apoptotic cells and modified lipid), angiogenesis, adhesion, inflammation, cardiomyopathy, diabetes and by: 9.

Clinical evidence has shown that disorders of lipid metabolism are associated with the pathogenesis of atherosclerosis [31, 32].

An oxidized form of LDL (ox-LDL) has been reported to disturb redox. Note: If you're looking for a free download links of Lipoprotein Metabolism and Atherogenesis Pdf, epub, docx and torrent then this site is not for you.

only do ebook promotions online and we does not distribute any free download of ebook on this site. Groups of rabbits, fed on Purina chow, were treated with cortisone acetate, hydrocortisone acetate or corticotropin. Fractionation and estimation of plasma lipids revealed high total and ester cholesterol, phospholipins and neutral fat, especially the latter.

Other groups of rabbits, fed on high-cholesterol diets, were similarly treated with cortisone or hydrocortisone and showed an increase of Cited by: Cardiovascular diseases are the main cause of death in the United States. Most of treatments that are currently used are low-fat diet (LFD) and statins.

However, alternatives have been proposed such as low-carbohydrate diets (LCD) and other drug treatments such as the use of inhibitors of secretory phospholipase A2 (i-sPLA2). Thus, in order to test whether they are an adequate alternative, two Author: Jose Oyama Moura Leite.

This publication presents in book form 84 papers presented at a symposium on Drugs Affecting Lipid Metabolism held in Milan, Italy, in Although the conference was international in scope and included contributions from most of the laboratories with active programs in lipid metabolism, better than 75% of the papers are in : Lemuel D.

Wright. INVITED COMMEN TARY Are Nuclear Factors the Ultimate Targets of Drugs Affecting Lipid Metabolism. Jean-Charles Fruchart, Pharm D, PhD Address and in secondary prevention.

They mainly act by decreasing Département d’Athérosclérose, INSERM U, Institut Pasteur atherogenic lipoprotein plasma concentrations (LDL- et Université de Lille 2, 1 rue du Professeur Calmette, BP.

provides accurate and independent information on more t prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Data sources include IBM Watson Micromedex (updated 4 May ), Cerner Multum™ (updated 4 May ), 4/   Glucose and Lipid Metabolism in the Human Arteriosclerotic Aorta.- Cholesterol Transfer in Vitro Between the Rabbit Aorta and Serum Lipoproteins.- Arterial Lipid Metabolism in Diabetic Animal Models with Reduced or Elevated Plasma Insulin Levels.- Lipid Metabolism in Perfused Human Coronary Arteries and Saphenous Veins.- IV.

Part 4: New Aspects of Lipoprotein Metabolism. Part 5: Fatty Acid, Lipase and Triglyceride Metabolism. Part 6: Reverse Cholesterol Transport - Regulation of Cholesterol Metabolism to Bile Acids. Part 7: Lp(a). Part 8: Antioxidants, Lipoproteins and Atherosclerosis. Part 9: Drugs Affecting Atherosclerosis and Thrombosis.

for those with high cholesterol only - must avoid if TG > mg b/c can elevate TG safety considerations for bile acid sequestrants GI effects - constipation, bloating, hemorrhoidal bleeding that reduce compliance.

Atherosclerosis is a disease in which the inside of an artery narrows due to the buildup of plaque. Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected.

Symptoms, if they occur, generally do not begin until middle cations: Coronary artery disease. The Canadian Cardiovascular Society (CCS) has published an important update to its guidelines for the management of dyslipidemia - lipid metabolism disorders – that can cause cardiovascular disease.

These disorders are very common, affect atherosclerosis-promoting lipids like cholesterol, and are a major target of widely used drugs like statins. Lipid disorders encompass a broad spectrum of metabolic conditions that affect blood lipid levels. They are generally characterized by elevated levels of cholesterol, triglycerides, and/or lipoproteins in the blood in association with an increased risk of (or current) cardiovascular disease.

The majority of lipid disorders are acquired through unhealthy lifestyles (obesity, inactivity. Moreover, immune cells have reported to be able to affect lipid metabolism. Summary In this review, we will summarize the latest findings on the interactions between lipids and the immune system, and we will discuss the potential consequences of these novel insights for future therapies for by:.

Overview Order Now Program Overview The National Lipid Association (NLA) developed the National Lipid Association Self-Assessment Program (NLA-SAP) to provide a critical assessment of your knowledge and to guide you in the selection of additional training courses as well as prepare you for certification as a Lipid Specialist.

The NLA-SAP will evaluate your clinical knowledgeMissing: Drugs. It is controversial whether SCH can lead to increased risks of cardiovascular (CV) disease and whether treatment with L-thyroxine reverses these risks.

The present study was designed to evaluate the effect of L-thyroxine treatment in SCH on lipid profile, atherosclerosis, endothelial function, serum inflammatory factors and adipocytokines. "Those results led us down the road to find the link between PPAR-g and lipid accumulation in atherosclerotic plaque." These subsequent papers provided a novel mechanism to explain how oxidized lipids could directly regulate gene expression and lipid metabolism in macrophages and potentially influence the development of the lesion.

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